Overview
MK-677 (Ibutamoren) is an oral growth hormone secretagogue that provides sustained GH and IGF-1 elevation for up to 24 hours. Unlike injectable peptides, it can be taken orally, making it convenient for long-term use.
How It Works
MK-677 mimics ghrelin and binds to ghrelin receptors, stimulating GH release. Unlike peptides, it has excellent oral bioavailability and a long half-life, providing sustained 24-hour effects from a single dose.
Research Status
Reached Phase 2 clinical trials. Shows promise for muscle wasting and osteoporosis. Not FDA approved.
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Related Peptides
Ipamorelin
Ipamorelin is a selective growth hormone secretagogue that stimulates the pituitary gland to release growth hormone without significantly affecting other hormones like cortisol or prolactin.
GHRP-2
GHRP-2 is a potent growth hormone secretagogue similar to GHRP-6 but with less appetite stimulation. It provides strong GH release while being more suitable for those who don't want increased hunger.
CJC-1295
CJC-1295 is a synthetic growth hormone-releasing hormone (GHRH) analog that increases growth hormone and IGF-1 levels. Available with or without DAC (Drug Affinity Complex) for different release profiles.