LL-37
Buy NowAlso known as: Cathelicidin, CAP-18, Human Antimicrobial Peptide
Overview
LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino acid cationic peptide derived from hCAP18. It exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi while modulating immune responses and promoting wound healing.
How It Works
LL-37 disrupts bacterial cell membranes through its positive charge (+6), creating transmembrane pores that cause cell lysis. It also binds to host receptors (FPRL-1, P2X7, EGFR) to boost chemotaxis, cell proliferation, and immunoregulation. Unlike traditional antibiotics, bacteria rarely develop resistance to it.
Research Status
Extensive research in antimicrobial applications. Not FDA approved. Published studies available on PubMed (PMC8227053).
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BPC-157 is a synthetic peptide derived from a protein found in stomach acid. It's known for its remarkable healing properties, particularly for muscles, tendons, and the digestive system.
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Thymosin Alpha-1 is a naturally occurring peptide that plays a crucial role in immune system regulation. It enhances T-cell function and has anti-viral and anti-fungal properties.